“Even patients in their twenties have symptoms of brain fog, fatigue, chronic inflammation, and chronic infection post-Covid,” Khan says. In her clinical experience, some report improvements in energy, mental clarity, migraines, and circadian disruption after using NAD-related therapies, especially during periods of high physical or cognitive stress. “I have a lot of fitness enthusiasts [as…

About a decade ago, many media outlets—including WIRED—zeroed in on a weird trend at the intersection of mental health, drug science, and Silicon Valley biohacking: microdosing, or the practice of taking a small amount of a psychedelic drug seeking not full-blown hallucinatory revels but gentler, more stable effects. Typically using psilocybin mushrooms or LSD, the…